Some interesting facts about bilirubin.
First of all, what is bilirubin? Bilirubin is a yellow chemical compound which is created when our red blood cells collapse. Then, most of it is then removed throughout excrement after our liver has changed its chemical composition.
On May 2, a group of researchers from different and among the best universities in the US published on Journal of the American Heart Association the study titled: “Bilirubin Is Inversely Associated With Cardiovascular Disease Among HIV‐Positive and HIV‐Negative Individuals in VACS (Veterans Aging Cohort Study)”.
Even though it is not a completed scientific fact, we learn from WebMD that if there is too much bilirubin then maybe our liver is not clearing all of it correctly or maybe our red blood cells are collapsing faster than usual. On the other hand, scientists from the above-mentioned study claim that bilirubin may have some cardiovascular benefits. Even though there are several different research and studies about the effect and role of bilirubin, the above-mentioned one is an added value to the list of studies and helps a lot in better future understanding of this chemical compound and its benefits.
The study’ methods.
The study had almost 100 thousand participants and they were all veterans, some with HIV and some without the infection. Researchers were able to have all these participants from the Veterans Aging Cohort Study which is a national observing of HIV infection which is also backed by the National Institute of Health (NIH). The average age of participants was 48 years, half of them were Afro-Americans while HIV-positive were 31418 and HIV-negative were 66987 of the participants. Further, participants were divided into four groups by comparing their bilirubin levels.
The study observed that the higher was the level of bilirubin the fewer chances a participant had to have cardiovascular problems like heart failure, stroke etc. Compared with the group which had the lowest levels of bilirubin, the group which had the highest bilirubin levels tend to have 23 percent fewer chances of cardiovascular problems. This looks very significant, doesn’t it? Probably yes but on the other hand, scientists, like the leader Vincent Marconi, point out that excess levels of bilirubin do not show significant improvement in relation to cardiovascular problems. In contrary, normal levels tended to show better improvements.
As a conclusion, we read from the authors that: This work provides an epidemiological rationale for future studies to investigate how the antioxidant effect of bilirubin could be harnessed to reduce chronic disease morbidity risk. Future studies should explore the use of bilirubin as a biomarker for other inflammation‐mediated conditions and all‐cause mortality.